ArticleRNA biology2026
PrfH accelerates repair of colicin E3 - damaged translating ribosomes by RtcB2.
Tinashe P Maviza, Nadezhda R Burmistrova, Aleksandr A Grachev, Elizaveta Khisambeeva, Dmitrii I Shiriaev, Anastasiia S Zarechenskaia, Alena Paleskava, Andrey L Konevega, Olga A Dontsova, Petr V Sergiev
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In one paragraphArticle in RNA biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
Tinashe P MavizaCenter for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Skolkovo, Russia.
Nadezhda R BurmistrovaFaculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
Aleksandr A GrachevMolecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC "Kurchatov Institute", Gatchina, Russia.
Elizaveta KhisambeevaCenter for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Skolkovo, Russia.
Dmitrii I ShiriaevFaculty of Chemistry, Lomonosov Moscow State University, Moscow, Russia.
Anastasiia S ZarechenskaiaCenter for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Skolkovo, Russia.
Alena PaleskavaMolecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC "Kurchatov Institute", Gatchina, Russia.
Andrey L KonevegaCenter for Integrative Structural Biology, National Research Centre "Kurchatov Institute", Moscow, Russia.
Olga A DontsovaCenter for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Skolkovo, Russia.
Petr V SergievCenter for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Skolkovo, Russia.ORCID 0000-0001-8866-1863 Funding
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6 · The paper itselfAbstract
Colicin E3 (E3-rRNAse) abolishes protein biosynthesis in bacteria by cleaving 16S rRNA in the decoding centre. The RtcB2-PrfH 16S rRNA repair module prevents cellular death upon exposure to E3-rRNAse in
Indexed as
ColicinsEscherichia coliEscherichia coli ProteinsPeptide Termination FactorsProtein BiosynthesisRibosomesRibosomal ProteinsRNA, Ribosomal, 16SColicinsEscherichia coli ProteinsPeptide Termination FactorsRibosomal Proteinsribosome releasing factorRNA, Ribosomal, 16Speptide hydrolysisRibosomeribosome rescuerRNA cleavagerRNA ligationtranslation
Identifiers
PMID42080441
PMCPMC13166195
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