Evidence map›Paper›PMID 42080405›Full record

ArticlePediatric transplantation2026

Donation After Circulatory Death in Pediatric Heart Transplantation.

Sarah Dudley Grorud, Michael D Porter, Taufiek Konrad Rajab, R Jerome Dixon, Michael McCulloch, Firezer Haregu

Abstract read
In one paragraph

Article in Pediatric transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah Dudley GrorudPediatric Cardiology, University of Virginia Children's Hospital, Charlottesville, Virginia, USA.ORCID 0009-0000-0052-3774
Michael D PorterData Science, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-9316-3578
Taufiek Konrad RajabCardiovascular Surgery, Arkansas Children's Hospital, Little Rock, Arkansas, USA.ORCID 0000-0001-8885-2758
R Jerome DixonData Science, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-8622-0597
Michael McCullochPediatric Cardiology, University of Virginia Children's Hospital, Charlottesville, Virginia, USA.ORCID 0000-0003-4837-6819
Firezer HareguPediatric Cardiology, University of Virginia Children's Hospital, Charlottesville, Virginia, USA.ORCID 0009-0008-0173-5128

Funding

AHRQ HHS R21 HS029548Jefferson Trust AHRQ 1R21HS029548-01A1
6 · The paper itself

Abstract

purposeDonation after circulatory death (DCD) is an emerging heart transplantation (HT) strategy with improved waitlist and comparable post-transplant outcomes to donation after brain death (DBD) in adults. Pediatric DCD-HT is underutilized but gaining broader adoption. We assessed the impact of DCD listing on waitlist outcomes and graft survival in pediatric HT.

methodsWe queried the OPTN (Organ Procurement and Transplantation Network)/UNOS (United Network for Organ Sharing) database for all pediatric primary isolated HT candidates between January 2021 and June 2024. Waitlist outcomes were compared by final listing type to account for crossovers. Offer dynamics were assessed by average interval between offers stratified by OPTN/UNOS status. Multivariable regression modeled offer frequency as a function of DCD listing. We compared 30-day survival between recipients of DCD and DBD organs.

resultsAmong 2486 candidates, 86 were initially listed eligible for DCD and 2400 for DBD. DCD candidates had higher clinical acuity than DBD candidates. DCD listing was associated with significantly shorter intervals between offers across all statuses and increased offer rate by 134% (95% CI: 92%-186%). Waitlist outcomes did not differ significantly by final listing type. There was no difference in 30-day survival between DCD and DBD recipients.

conclusionsDCD listing in pediatric HT is associated with a shorter interval between offers and more frequent offers. Waitlist survival was similar between groups despite DCD candidates being sicker at listing. There was no difference in 30-day survival between DCD and DBD recipients. These findings suggest that broader adoption of pediatric DCD-HT can expand access to donor hearts without compromising early post-transplant outcomes.

Indexed as

Heart TransplantationTissue and Organ ProcurementTissue DonorsAdolescentChildChild, PreschoolDatabases, FactualFemaleGraft SurvivalHumansInfantMaleRetrospective StudiesWaiting Listsdonation after circulatory deathpediatric heart transplantationtransplant outcomeswaitlist outcomes

Identifiers

PMID42080405
PMCPMC13137765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.