Evidence map›Paper›PMID 42080300›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

Decision aid reduces caregivers' preference for acid-suppressive medication in infants with symptoms suggestive of reflux.

Anna de Geus, Marinde van Lennep, Quirine M van Dellen, Andrieke C Knottnerus, Sarah T A Teklenburg-Roord, Marc A Benninga, Merit M Tabbers

Abstract read
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Anna de GeusDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-2282-0128
Marinde van LennepDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Quirine M van DellenDepartment of Pediatrics, Onze Lieve Vrouw Gasthuis (OLVG), Amsterdam, the Netherlands.
Andrieke C KnottnerusDepartment of Pediatrics, Spaarne Gasthuis, Hoofddorp, the Netherlands.
Sarah T A Teklenburg-RoordDepartment of Pediatrics, Isala, Zwolle, the Netherlands.
Marc A BenningaDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Merit M TabbersDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0001-9744-7308

Funding

Zorginstituut Nederland
6 · The paper itself

Abstract

objectivesCaregivers of infants with symptoms suggestive of gastroesophageal reflux (GER), such as regurgitation and excessive crying, often feel uncertain and seek treatment, though it is usually unnecessary. This study evaluated the effect of a decision aid on reducing caregivers' preference for acid suppressive medication for infants referred because of potential GER symptoms and its effect on their decision certainty.

methodsInfants (<18 months) referred to pediatric outpatient clinics with symptoms suggestive of GER were included. The decision aid provided information on gastroesophageal reflux disease (GERD) and three treatment options: lifestyle advice, thickened feeding, and acid-suppressive medication. Caregivers completed questionnaires assessing treatment preference and decision certainty before (T1a) and after using the decision aid (T1b), and after the outpatient visit (T2). Decision certainty was assessed using the Decisional Conflict Scale (DCS).

resultsA total of 110 infants were included (median age 4 months [interquartile range 2-6]; 48% female; 78% general hospital). Pre-visit questionnaires (T1a, T1b) were completed by 79 caregivers (72%) and 53 (48%) also completed T2. Preference for acid-suppressive medication decreased from 46/79 (58%) at T1a to 34/79 (43%) at T1b (p < 0.05), and to 6/53 (11%) at T2 (p < 0.001). Mean DCS-score (scale 0-100) decreased from 47.2 (standard deviation [SD] 16.1) at T1a to 34.4 (SD 17.4) at T1b, and to 19.0 (SD 12.3) post-visit (p < 0.001), indicating improved decision certainty.

conclusionsThe decision aid reduced caregivers' preference for acid-suppressive treatment in infants with symptoms suggestive of GER and increased decision certainty. This supports the potential role of a decision aid in promoting appropriate care.

Indexed as

CaregiversDecision Support TechniquesGastroesophageal RefluxProton Pump InhibitorsDecision MakingFemaleHumansInfantMalePatient PreferenceSurveys and QuestionnairesProton Pump Inhibitorsdecision certaintygastroesophageal refluxpediatricsshared decision makingtreatment

Identifiers

PMID42080300
PMCPMC13446632

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.