Evidence map›Paper›PMID 42080077›Full record

ArticleInternational journal of medical sciences2026

Mediation of Pre-Pregnancy Body Mass Index and Dietary Patterns with Relation to Vitamin D and Erythropoiesis-Related Micronutrients in Pregnant Women.

Nhi Thi Hong Nguyen, Chien-Yeh Hsu, Chyi-Huey Bai, Jung-Su Chang, Yi-Chun Chen, Ya-Li Huang, Fan-Fen Wang, Arpita Das, Jane C-J Chao

Abstract read
In one paragraph

Article in International journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nhi Thi Hong NguyenSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.
Chien-Yeh HsuDepartment of Information Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Chyi-Huey BaiDepartment of Public Health, School of Medicine, Taipei Medical University, Taipei, Taiwan.
Jung-Su ChangSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.
Yi-Chun ChenSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.
Ya-Li HuangDepartment of Public Health, School of Medicine, Taipei Medical University, Taipei, Taiwan.
Fan-Fen WangDepartment of Internal Medicine, Yangming Branch, Taipei City Hospital, Taipei, Taiwan.
Arpita DasCenter for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
Jane C-J ChaoSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pre-pregnancy body mass index (BMI) and dietary patterns (DPs) have been linked to serum erythropoiesis-related micronutrients (iron, folate, and vitamin B12). We studied the mediating effects of pre-pregnancy BMI and DPs on the association of serum vitamin D with the levels of erythropoiesis-related micronutrients. A cross-sectional research involving 1485 pregnant women was carried out in hospitals and clinics between 2017 and 2019 using the Nationwide Nutrition and Health Survey in Taiwan. Dietary intake was measured using food frequency questionnaire, and DPs were identified utilizing principal component analysis. Serum vitamin D and iron biomarker levels were examined. A mediation analysis was conducted to investigate the mediating effects of pre-pregnancy BMI and DPs on the association of serum vitamin D levels with erythropoiesis-related micronutrient levels. Serum 25(OH) vitamin D was positively linked to erythropoiesis-related micronutrient levels. Pre-pregnancy BMI partially mediated the association between serum 25(OH) vitamin D and serum iron (indirect effect: -0.004, 95% confidence interval (CI): -0.009, 0.000), folate (indirect effect: -0.009, 95% CI: -0.021, 0.000), and vitamin B12 levels (indirect effect: -0.137, 95% CI: 0.282, -0.02). Animal and staple-based DP and mushrooms, roots, and dairy DP mediated the association between serum 25(OH) vitamin D and serum iron levels (indirect effect: -0.004, 95% CI: -0.009, 0.000 and indirect effect: -0.004, 95% CI: 0.009, 0.000, respectively). Pre-pregnancy BMI mediates the association of serum vitamin D with erythropoiesis-related micronutrients. Animal and staple-based DP and mushrooms, roots, and dairy DP mediate the association between serum vitamin D and iron status.

Indexed as

Body Mass IndexDietErythropoiesisMicronutrientsVitamin DAdultCross-Sectional StudiesFemaleFolic AcidHumansIronNutrition SurveysPregnancyTaiwanVitamin B 12Folic AcidIronMicronutrientsVitamin B 12Vitamin Ddietary patterniron biomarkersmediating effectpregnant womenserum vitamin D

Identifiers

PMID42080077
PMCPMC13133886

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.