ArticleJTCVS open2026
Atrial fibrillation worsens outcome of mitral valve repair for degenerative mitral regurgitation: Long-term follow-up of 959 patients.
Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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20 authors.
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Abstract
Background: The prognostic significance of atrial fibrillation (AF) in patients with degenerative mitral regurgitation (MR) undergoing mitral valve (MV) repair remains controversial. The association between preexisting AF and long-term clinical and echocardiographic outcomes following mitral repair was analyzed. Methods: This retrospective study included 959 patients (mean age, 60 ± 12 years) who underwent MV repair for degenerative MR between 2001 and 2022. Patients were stratified by preoperative rhythm: 670 in sinus rhythm and 289 with AF. Serial echocardiographic changes were assessed using linear mixed models. The mean follow-up was 8.6 ± 5.4 years (8219 patient-years). Results: Compared to patients with sinus rhythm, those with AF were older, more symptomatic, and exhibited greater cardiac remodeling, prompting higher rates of concomitant tricuspid annuloplasty (45% vs 5.7%) and ablation procedures (91% vs 0%) ( Conclusions: These findings indicate that AF identifies a higher-risk phenotype characterized by advanced atrial disease and persistent hemodynamic burden following MV repair. Future studies are needed to determine whether intervention before the development of advanced atrial remodeling or AF can improve long-term outcomes.
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