Evidence map›Paper›PMID 42079968›Full record

ArticleJTCVS open2026

Rethinking timing: Outcomes of late versus early surgical repair of complete atrioventricular septal defect in a resource-limited setting.

Andres F Jimenez, Laura Sanchez, Ivone Pineda, Lina Ramirez, Tomas Chalela, Carlos Obando, Jaime Camacho, Nestor Sandoval

Abstract read
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andres F JimenezDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.
Laura SanchezDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.
Ivone PinedaDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.
Lina RamirezDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.
Tomas ChalelaDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.
Carlos ObandoDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.
Jaime CamachoDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.
Nestor SandovalDepartment of Cardiovascular Surgery, Fundación Cardioinfantil - La Cardio, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Complete atrioventricular septal defect (CAVSD) repair is ideally performed within the first 6 months of life; however, in resource-limited settings, access barriers often delay surgery We compared outcomes between early (<6 months) and late (≥6 months) surgical repair at a single reference center in Colombia. Methods: A retrospective cohort of 111 consecutive patients (2012-2022) undergoing primary CAVSD repair was analyzed. Patients were divided into early (n = 22) and late (n = 89) groups. Preoperative, intraoperative, and postoperative variables-including operative mortality, survival, and freedom from left atrioventricular valve (LAVV) reintervention-were compared using χ Results: Median age at surgery was 4.9 months (interquartile range, 4.5-5.4) for early versus 8.5 months (interquartile range, 7.2-14.3) for late repair. Trisomy 21 was present in 83.8%. The early group had greater preoperative oxygen saturation ( Conclusions: In this cohort, later CAVSD repair yielded operative mortality and medium-term outcomes comparable with early repair despite less-favorable preoperative profiles. These findings may support flexible surgical timing in resource-limited settings with robust perioperative care and follow-up.

Indexed as

complete atrioventricular septal defectcongenital heart diseaseoutcomespediatric cardiac surgerypulmonary hypertensionresource-limited settingsurgical timing

Identifiers

PMID42079968
PMCPMC13131169

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.