ArticleJTCVS open2026
The impact of perioperative outcomes on long-term survival after esophageal cancer resection.
Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Current metrics for quality of care after esophagectomy rely on short-term perioperative outcomes. We aimed to evaluate the relationship of perioperative outcomes and long-term survival after esophagectomy for esophageal cancer. Methods: Institutions in the National Cancer Database performing ≥20 esophagectomies (2010-2019) were ranked by a weighted composite score of major perioperative events-length of stay >20 days, unplanned readmissions, and 30-day mortality-and stratified into quintiles. Survival between centers with the least perioperative morbidity (quintile 1) and all other centers (quintiles 2-5) was compared using Kaplan-Meier, Cox proportional hazard, and landmark analyses. Results: Overall, 11,036 patients with esophageal cancer who underwent esophagectomy at 209 institutions were included. Of those, 1825 (17%) patients were treated at 42 quintile 1 centers and 9211 (83%) were treated at 167 quintiles 2-5 centers. Prolonged length of stay (15% vs 7.9%, Conclusions: Our study demonstrates that patients undergoing esophagectomy for esophageal cancer at centers with lower rates of major perioperative events had improved long-term survival, suggesting that short-term metrics can serve as indicators of long-term performance and oncologic efficacy.
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