ArticleNeuro-oncology advances
Patient preferences for incidental findings in a genomic trial: Insights from the Copenhagen glioblastoma cohort.
Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Glioblastoma (GBM) patients often face cognitive impairment, which may limit their capacity to comprehend complex trial information, particularly regarding genomic analyses and incidental findings. We analyzed consent forms from a genomic study, including 108 newly diagnosed grade 4 GBM patients in the Danish Glioblastoma Cohort (2016-2019) undergoing whole-exome sequencing. Of 110 patients, 108 (98.2%) consented. Preferences for incidental findings varied: 31% chose no information, 22% actionable findings only, and 42% all information. Despite the complexity, participation was high, suggesting that GBM patients are willing and able to participate in genomic research when flexible consent options are offered.
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