Trajectories of Medication Utilization for Opioid Use Disorder in Pregnancy and Associated Maternal Outcomes.

Yi Wang, M Luke Smith, Deborah B Ehrenthal

Abstract read

In one paragraph

Article in O&G open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yi WangSilberman School of Social Work, Hunter College, City University of New York, New York, New York; and the Social Science Research Institute, and the Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, Pennsylvania.

M Luke SmithSilberman School of Social Work, Hunter College, City University of New York, New York, New York; and the Social Science Research Institute, and the Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, Pennsylvania.

Deborah B EhrenthalSilberman School of Social Work, Hunter College, City University of New York, New York, New York; and the Social Science Research Institute, and the Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, Pennsylvania.

Funding

Prenatal Opioid Exposure: Birth, health, socioeconomic, and educational outcomes of mothers and their childrenR01HD102125 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI BERGER, LAWRENCE M, EHRENTHAL, DEBORAH BETH · 2020 to 2024

$2.2M

NICHD NIH HHS R01 HD102125

6 · The paper itself

Abstract

objectiveTo characterize distinct medications for opioid use disorder (MOUD) trajectories during pregnancy and evaluate their associations with adverse perinatal maternal outcomes.

methodsA retrospective cohort study was conducted among Wisconsin Medicaid-covered singleton births from 2011 to 2019. Primary outcomes were intensive care unit (ICU) admission, an emergency department (ED) visit, and severe maternal morbidity (SMM) from delivery through 6 weeks postpartum. Weekly MOUD use during gestation was classified into trajectories by using repeated measures latent class analysis. Associations between MOUD trajectory and outcomes were estimated by using logistic regression after propensity score matching.

resultsOf 4,442 pregnant individuals with opioid use disorder, 2,944 (66.3%) received MOUD and 1,498 (33.7%) did not receive MOUD. Four trajectories were identified: 1) consistent treatment (n=1,387), 2) early initiation (n

conclusionConsistent treatment and early initiation of MOUD were associated with the most favorable maternal outcomes, whereas late initiation, declining engagement, or no treatment corresponded to higher odds of adverse outcomes. Findings support efforts to initiate MOUD early in pregnancy and maintain continuity through gestation.

Identifiers

PMID42079567

DOI10.1097/og9.0000000000000170

PMCPMC13134764

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.