Evidence map›Paper›PMID 42079402›Full record

ArticleFujita medical journal2026

Incidence and risk factors for peripheral intravenous catheter failure in Japanese neonatal intensive care units and growing care units: a multicenter observational study.

Shun Yamamoto, Ryoko Murayama

Abstract read
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Article in Fujita medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Shun YamamotoGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Ryoko MurayamaFaculty of Nursing, School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Peripheral intravenous catheters (PIVCs) are used in neonatal intensive care units (NICUs) and growing care units (GCUs). However, neonates/infants in these units frequently experience catheter failure (CF) because of complications, such as extravasation and phlebitis. Nonetheless, data on PIVCs from Japan remain limited. Therefore, this study aimed to investigate the use of infusion catheters and the incidence, characteristics, and risk factors of PIVC-related catheter failure in Japanese NICUs and GCUs. Methods: This study was conducted between August 2024 and February 2025 using cross-sectional and prospective surveys. Data from 600 hospitalized neonates/infants and 259 PIVC cases were analyzed. CF was defined as unplanned catheter removal before the completion of therapy owing to loss of function or an inability to administer fluids. Results: Overall, 48.0% of neonates/infants had infusion catheters. The incidence proportion of CF was 47.1%, with an incidence density of 173.1/1,000 catheter-days. Extravasation was the most frequently identified cause of CF (95.9%), and swelling and leaking were primary symptoms. Multivariate Cox regression showed that gestational age (hazard ratio=0.96, p=.03) and infusion flow volume at the time of PIVC removal (hazard ratio=1.28/1 mL/h, p<.01) were significant risk factors. Long PIVCs had significantly longer dwell times than PIVCs (log-rank p=.01). Conclusions: CF is highly prevalent in Japanese infants in NICUs/GCUs, with a rate similar to that reported internationally. Long PIVCs may help extend the catheter dwell times. These findings highlight the need for standardized prevention strategies and improved catheter management protocols.

Indexed as

Catheter failureJapanMulticenter observational studyNICUPeripheral intravenous catheter

Identifiers

PMID42079402
PMCPMC13129708

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