Evidence map›Paper›PMID 42079401›Full record

ArticleFujita medical journal2026

Feasibility of using a pocket-sized ultrasound imaging device for detecting insulin-derived amyloidosis-like findings in patients with diabetes mellitus: a preliminary study.

Naoko Kageura, Hiroji Takai, Yasuo Takatsu, Atsushi Suzuki, Shigeki Kobayashi, Kazuki Takano, Ayano Nakai, Junko Sugama, Kimie Takehara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fujita medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Naoko KageuraGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Hiroji TakaiDepartment of Radiology, Fujita Health University Hospital, Toyoake, Aichi, Japan.
Yasuo TakatsuDepartment of Medical Science and Molecular Imaging, Clinical Education Collaboration Unit, School of Medical Science, Fujita Health University, Toyoake, Aichi, Japan.
Atsushi SuzukiDepartment of Endocrinology, Metabolism and Diabetes, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.
Shigeki KobayashiDepartment of Radiological Technology, Clinical Education Collaboration Unit, School of Medical Science, Fujita Health University, Toyoake, Aichi, Japan.
Kazuki TakanoDepartment of Medical Science and Molecular Imaging, Clinical Education Collaboration Unit, School of Medical Science, Fujita Health University, Toyoake, Aichi, Japan.
Ayano NakaiFaculty of Nursing, School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Junko SugamaCenter for Nursing Research and Social Implementation, Innovation Promotion Division, Research Promotion Headquarters, Fujita Health University, Toyoake, Aichi, Japan.
Kimie TakeharaFaculty of Nursing, School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Insulin-derived amyloidosis (IDA) reduces insulin absorption, increasing the risk of poor glycemic control; however, early detection remains challenging. Although ultrasound can identify IDA, the effectiveness of portable pocket-sized devices has not been evaluated. This study was performed to evaluate the detectability of findings suggestive of IDA using a pocket-sized ultrasound device on the abdominal region, the most common site for stable insulin absorption in patients with diabetes mellitus. Methods: This cross-sectional observational study was conducted in the diabetes ward of a university hospital between July and December 2024. The participants were inpatients with diabetes who had been receiving insulin injections for more than 1 month. Findings suggestive of IDA were assessed through visual inspection and palpation, magnetic resonance imaging (MRI), high-performance ultrasonography, and a pocket-sized ultrasound device. The concordance rate between the pocket-sized ultrasound device and other assessment methods was calculated. Results: Of the 20 participants enrolled, 5 met the exclusion criteria; thus, data from 15 participants were included in the final analysis. Findings suggestive of IDA were identified in nine patients (60.0%) by visual inspection and palpation and in eight patients (53.3%) by the pocket-sized ultrasound device, high-performance ultrasound, and MRI. The concordance rate among the pocket-sized ultrasound device, high-performance ultrasound, and MRI was 100%, while the concordance rate between visual inspection with palpation and the pocket-sized ultrasound device was 80%. Conclusions: These findings suggest that a pocket-sized ultrasound device has the potential to detect findings suggestive of IDA and may be suitable for use in clinical practice.

Indexed as

High-performance ultrasoundInsulin-derived amyloidosisInsulin injectionMagnetic resonance imagingPocket-sized ultrasound

Identifiers

PMID42079401
PMCPMC13129715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.