Evidence map›Paper›PMID 42079335›Full record

ArticleFrontiers in neuroinformatics2026

A deep learning based NeuroFusionNet approach for automated brain tumor diagnosis from MRI.

Omara Mustafa, Salem Alhatamleh, Hamad Yahia Abu Mhanna, Abdallah Almahmoud, Rami Malkawi, Majd Malkawi, Abdel-Baset Bani Yaseen, Hanan Fawaz Akhdar, Hatem Malkawi, Fatimah Maashey and 2 more

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Article in Frontiers in neuroinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Omara MustafaDepartment of Radiology, Korean Medical Center, Lusail, Qatar.
Salem AlhatamlehComputer Science Department, Faculty of Information Technology and Computer Sciences, Yarmouk University, Irbid, Jordan.
Hamad Yahia Abu MhannaDepartment of Medical Imaging, Faculty of Allied Medical Sciences, Isra University, Amman, Jordan.
Abdallah AlmahmoudDepartment of Allied Medical Sciences-Radiologic Technology, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Rami MalkawiDepartment of Information Systems, Faculty of Information Technology and Computer Science, Yarmouk University, Irbid, Jordan.
Majd MalkawiFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Abdel-Baset Bani YaseenDepartment of Medical Imaging, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan.
Hanan Fawaz AkhdarPhysics Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Hatem MalkawiFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Fatimah MaasheyPhysics Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Latifah AlghulayqahPhysics Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Mohammad AminComputer Science Department, Faculty of Information Technology and Computer Sciences, Yarmouk University, Irbid, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brain tumor diagnosis from magnetic resonance imaging (MRI) remains a challenging task due to the high variability in tumor appearance and the limitations of manual interpretation. Methods: To address these challenges, this paper proposes NeuroFusionNet, a deep learning framework for automated brain tumor classification from MRI. The framework integrates GAN-based synthetic image generation with transfer learning using a fine-tuned VGG16 backbone. Real and GAN-generated MRI images are passed through VGG16 to extract discriminative feature representations, which are then used for final classification. To adapt the model to domain-specific MRI characteristics while preserving pretrained knowledge, the last ten layers of VGG16 are fine-tuned and the remaining layers are kept frozen. Results: The effectiveness of NeuroFusionNet is validated on two publicly available brain MRI datasets. Experimental results demonstrate that the proposed learning framework achieves classification accuracies of 99.05 and 98.75% on the Brain Tumor MRI Dataset and the MRI with Bounding Boxes Dataset, respectively, consistently outperforming several state-of-the-art neural architectures, including VGG16, VGG19, MobileNetV2, DenseNet121, and NASNetLarge. Conclusion: The results suggest that NeuroFusionNet is effective for the evaluated public MRI datasets; additional external validation is required.

Indexed as

artificial intelligencebrain tumor classificationdeep learninggenerative adversarial networkMRI imageVGG16

Identifiers

PMID42079335
PMCPMC13131096

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