Evidence map›Paper›PMID 42079218›Full record

ArticlebioRxiv : the preprint server for biology2026

TAR syndrome causal gene

Jennifer Mott, Zifei Pei, Jiawan Sun, Choong Heon Lee, Twishi Puri, Zander M Sachs, Ana Aviles Vargas, Nicholas Blaha, Mabel Tong, Aimin Liu and 5 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jennifer MottDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-3506-6929
Zifei PeiDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.
Jiawan SunDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0009-0000-7904-5145
Choong Heon LeeBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY 10016, USA.
Twishi PuriDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.
Zander M SachsDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.
Ana Aviles VargasDepartment of Biomedical Engineering, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0009-0000-8864-6241
Nicholas BlahaDepartment of Neuroscience and Experimental Therapeutics, College of Medicine, Pennsylvania State University, Hershey, PA 17033, USA.
Mabel TongDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0009-0001-7759-9627
Aimin LiuDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-0099-0879
Yong WangDepartment of Biomedical Engineering, Pennsylvania State University, University Park, PA 16802, USA.
Yongsoo KimDepartment of Neuroscience and Experimental Therapeutics, College of Medicine, Pennsylvania State University, Hershey, PA 17033, USA.ORCID 0000-0002-4277-0279
Santhosh GirirajanDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-0598-4945
Jiangyang ZhangBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-0740-2662
Yingwei MaoDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0001-7339-1565

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Cross Scale Interrogation of NPD Genes (SING) in miceRM1MH138309 · NIMH · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VIVEK KUMAR, Yongsoo Kim · 2025 to 2026
$7.3M
Research Training in Physiological Adaptations to StressT32GM108563 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T, KORZICK, DONNA HOPE · 2014 to 2023
$2.2M
Translational control in neurogenesis by ZNF804AR01MH122556 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI MAO, YINGWEI, SHI, YONGSHENG · 2020 to 2024
$1.7M
Dissecting the neuroprotective role of an RNA binding protein in neurodegenerationR21AG094078 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI MAO, YINGWEI · 2025 to 2025
$429k
Delineating molecular mechanism of developmental defects of TAR syndromeR21DE032806 · NIDCR · PENNSYLVANIA STATE UNIVERSITY, THE · PI MAO, YINGWEI · 2023 to 2023
$412k
Dissecting functional roles of schizophrenia risk gene ZNF804a in neural developmentR21MH108983 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI MAO, YINGWEI · 2016 to 2017
$406k
NCATS NIH HHS UL1 TR002014NIA NIH HHS R21 AG094078NIDCR NIH HHS R21 DE032806NIGMS NIH HHS T32 GM108563NIMH NIH HHS R01 MH122556NIMH NIH HHS R21 MH108983NIMH NIH HHS RM1 MH138309
6 · The paper itself

Abstract

RNA-Binding Motif Protein 8A (RBM8A) is a core component of the exon junction complex (EJC), which plays a fundamental role in post-transcriptional RNA regulation. Mutations in the

Indexed as

Hedgehog signalinglimb developmentosteogenesisprimary ciliaRBM8Athrombocytopenia-absent radius (TAR) syndrome

Identifiers

PMID42079218
PMCPMC13131530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.