Evidence map›Paper›PMID 42079193›Full record

ArticlebioRxiv : the preprint server for biology2026

Myeloid Cell States in Influenza-Associated Pulmonary Aspergillosis Are Shaped by Iron Overload and Metabolic Reprogramming.

Madeleine S Grau, Brian P Jackson, Carol Ringelberg, Fred W Kolling, George S Deepe, Robert A Cramer, Joshua J Obar

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Madeleine S GrauGeisel School of Medicine at Dartmouth, Department of Microbiology & Immunology, Lebanon, NH 03756.
Brian P JacksonDartmouth College, Department of Earth and Planetary Sciences, Hanover, NH 03755.
Carol RingelbergGeisel School of Medicine at Dartmouth, Dartmouth Cancer Center, Lebanon, NH 03756.
Fred W KollingGeisel School of Medicine at Dartmouth, Dartmouth Cancer Center, Lebanon, NH 03756.
George S DeepeUniversity of Cincinnati College of Medicine, Division of Infectious Diseases, Cincinnati, OH 45267.
Robert A CramerGeisel School of Medicine at Dartmouth, Department of Microbiology & Immunology, Lebanon, NH 03756.
Joshua J ObarGeisel School of Medicine at Dartmouth, Department of Microbiology & Immunology, Lebanon, NH 03756.ORCID 0000-0003-4068-7911

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Zhao - Proj 2P20GM130454 · NIGMS · DARTMOUTH COLLEGE · PI MICHAEL L WHITFIELD · 2019 to 2026
$27.2M
IMMUNOBIOLOGY OF MYELOID AND LYMPHOID CELLST32AI007363 · NIAID · DARTMOUTH COLLEGE · PI Claudia V Jakubzick · 1990 to 2026
$9.5M
Development of an influenza A virus and Aspergillus fumigatus coinfection modelR21AI152019 · NIAID · DARTMOUTH COLLEGE · PI OBAR, JOSHUA J · 2020 to 2021
$451k
Acquisition of the NextSeq2000 Sequencing platform to Increase Next Generation Sequencing Throughput While Reducing Costs at DartmouthS10OD030242 · OD · DARTMOUTH COLLEGE · PI KOLLING IV, FRED W · 2021 to 2021
$321k
10X Genomics Chromium Single-cell Sequencing to Expand Research At DartmouthS10OD025235 · OD · DARTMOUTH COLLEGE · PI TOMLINSON, CRAIG R · 2018 to 2018
$125k
NCI NIH HHS P30 CA023108NIAID NIH HHS R21 AI152019NIAID NIH HHS T32 AI007363NIGMS NIH HHS P20 GM130454NIH HHS S10 OD025235NIH HHS S10 OD030242
6 · The paper itself

Abstract

Virus-associated pulmonary aspergillosis is a life-threatening secondary infection that substantially increases morbidity and mortality in critically ill patients with respiratory virus infections. Influenza A virus (IAV) and SARS-CoV2 are known to disrupt pulmonary homeostasis, the mechanisms by which these perturbations render the host susceptibility to

Indexed as

Aspergillus fumigatusinfluenza A virusironlungssecondary infection

Identifiers

PMID42079193
PMCPMC13131551

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.