Evidence map›Paper›PMID 42079049›Full record

ArticlebioRxiv : the preprint server for biology2026

Isoform-specific cofactor recruitment through the intrinsically disordered N-terminus of p63 underlies differential transcriptional activities.

Marina F Nogueira, Michael J Moore, Aparna R Biswas, Michael P Meers, Sidharth V Puram

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marina F NogueiraDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO USA.
Michael J MooreDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO USA.
Aparna R BiswasDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO USA.
Michael P MeersDepartment of Genetics, Washington University School of Medicine, St. Louis, MO USA.
Sidharth V PuramDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO USA.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
TrainingP41GM103422 · NIGMS · WASHINGTON UNIVERSITY · PI YARASHESKI, KEVIN E · 2012 to 2019
$12.0M
INSTITUTIONAL TRAINING GRANT IN GENOMIC SCIENCET32HG000045 · NHGRI · WASHINGTON UNIVERSITY · PI MICHAEL R BRENT, Barak A Cohen · 1997 to 2026
$8.4M
Deciphering epigenetically-regulated pathways to improve targeted therapy for invasion and metastasis in head and neck cancerR01DE032865 · NIDCR · WASHINGTON UNIVERSITY · PI Robi D Mitra, Sidharth Venkata Puram · 2023 to 2026
$2.4M
A Biomedical Mass Spectrometry Resource: Ongoing Driving Biomedical ProjectsR24GM136766 · NIGMS · WASHINGTON UNIVERSITY · PI GROSS, MICHAEL L · 2020 to 2022
$2.3M
Dissecting hybrid epithelial-mesenchymal states in head and neck cancerR01DE032371 · NIDCR · WASHINGTON UNIVERSITY · PI Sidharth Venkata Puram · 2023 to 2026
$1.6M
NCATS NIH HHS UL1 TR000448NCI NIH HHS P30 CA091842NHGRI NIH HHS T32 HG000045NIDCR NIH HHS R01 DE032371NIDCR NIH HHS R01 DE032865NIGMS NIH HHS P41 GM103422NIGMS NIH HHS R24 GM136766
6 · The paper itself

Abstract

The transcription factor p63 is critical for epithelial development and implicated in tumorigenesis. However, our understanding of the role of p63 in development and disease has been complicated by its diverse isoforms. As a member of the p53 family member of genes,

Identifiers

PMID42079049
PMCPMC13131546

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.