Evidence map›Paper›PMID 42079031›Full record

ArticleIranian journal of basic medical sciences2026

Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing.

Maziar Malekzadeh, Mehrdad Moosazadeh Moghaddam, Masoud Ghorbani

Abstract read
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In one paragraph

Article in Iranian journal of basic medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maziar MalekzadehTissue Engineering and Regenerative Medicine Research Center, New Health Technologies Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Mehrdad Moosazadeh MoghaddamTissue Engineering and Regenerative Medicine Research Center, New Health Technologies Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Masoud GhorbaniTissue Engineering and Regenerative Medicine Research Center, New Health Technologies Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Eliminating skin defects using scaffolds, especially hydrogels, has been a promising method to accelerate regeneration. The utilization of hydrogels composed of carboxymethyl chitosan and pullulan oxide, synthesized via Schiff base reaction, represents an effective approach for skin repair. Materials and Methods: Carboxymethyl chitosan was reacted with oxidized pullulan (CMCS/OPL), and the hydrogel was formed. In addition, an antibacterial peptide was incorporated into a hydrogel. In Results: Two groups of hydrogels exhibited the appropriate viscosity, porosity, and degradation. The rate of cell proliferation on the 7 Conclusion: These hydrogels represent a promising strategy to promote skin regeneration and provide a significant avenue for future clinical applications in regenerative medicine.

Indexed as

Carboxymethyl chitosanHydrogelOxidized pullulanSchiff base reactionSkin regeneration

Identifiers

PMID42079031
PMCPMC13135185

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.