Evidence map›Paper›PMID 42078595›Full record

ArticleAnnals of medicine and surgery (2012)2026

Analyzing the effects of anemia on the outcomes of mechanical thrombectomy in ischemic stroke patients: a systematic review and meta-analysis.

Mostafa Hossam El Din Moawad, Ibrahim Serag, Ibraheem M Alkhawaldeh, Ahmed F Gadelmawla, Mohammed Khaled Mohammed, Mohamed Samir A Zaki, Hamza A Abdul-Hafez, Mohamed Abouzid

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Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mostafa Hossam El Din MoawadClinical Pharmacy Department, Alexandria Main University Hospital, Alexandria, Egypt.
Ibrahim SeragFaculty of Medicine, Mansoura University, Mansoura, Egypt.
Ibraheem M AlkhawaldehFaculty of Medicine, Mutah University, Al-Karak, Jordan.
Ahmed F GadelmawlaFaculty of Medicine, Menoufia University, Menoufia, Egypt.
Mohammed Khaled MohammedFaculty of Medicine, Cairo University, Cairo, Egypt.
Mohamed Samir A ZakiDepartment of Anatomy, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Hamza A Abdul-HafezDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Mohamed AbouzidDepartment of Physical Pharmacy and Pharmacokinetics, Faculty of Pharmacy, Poznan University of Medical Sciences, Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anemia is a common yet often overlooked condition in patients with acute ischemic stroke (AIS) undergoing mechanical thrombectomy. Hemoglobin levels play a crucial role in oxygen transport, and their depletion may exacerbate ischemic injury and worsen functional outcomes. This meta-analysis aimed to evaluate the effect of anemia on the functional and survival outcomes of patients with AIS treated with mechanical thrombectomy. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we searched electronic databases (PubMed, Scopus, and Web of Science) to identify eligible studies reported up to January 2025. Using Review Manager software, we reported outcomes as odds ratios (ORs) or mean difference and confidence intervals (CIs). A Results: Nine retrospective cohort studies comprising 2189 patients were included. Anemia was significantly associated with lower odds of achieving good functional outcomes (OR = 0.30, 95% CI: 0.13-0.68, Conclusion: Anemia negatively impacted functional recovery and survival in patients with AIS undergoing mechanical thrombectomy. Given these findings, optimizing hemoglobin levels may be a potential strategy to improve patient outcomes. Further prospective studies are needed to explore the benefits of anemia correction strategies in stroke management.

Indexed as

anemiagood functional outcomeshemoglobinischemic strokemechanical thrombectomy

Identifiers

PMID42078595
PMCPMC13132313

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