Evidence map›Paper›PMID 42078589›Full record

ArticleJSES international2026

Promoting hematoma-like tissue formation in arthroscopic rotator cuff repair: impact of a bioinductive collagen implant.

Hideki Kinjo, Naoki Suenaga, Naomi Oizumi, Jun Kawamata, Kotaro Nishida

Abstract read
In one paragraph

Article in JSES international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hideki KinjoDepartment of Orthopedic Surgery, Graduate School of Medicine, University of Ryukyus, Okinawa, Japan.
Naoki SuenagaUpper Extremity Center of Joint Replacement and Endoscopic Surgery, Hokushin Orthopaedic Hospital, Sapporo, Hokkaido, Japan.
Naomi OizumiUpper Extremity Center of Joint Replacement and Endoscopic Surgery, Hokushin Orthopaedic Hospital, Sapporo, Hokkaido, Japan.
Jun KawamataDepartment of Orthopaedic Surgery, NHO Kochi National Hospital, Kochi, Japan.
Kotaro NishidaDepartment of Orthopedic Surgery, Graduate School of Medicine, University of Ryukyus, Okinawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hematomas, rich in platelet-derived growth factors, are vital in tendon-bone healing. Reportedly, larger hematoma-like tissue (HLT) surrounding the repaired tissue at 6-8 weeks after rotator cuff repair on T2-weighted magnetic resonance imaging effectively predicts structural outcomes (Sugaya classification type 1) at 6 months post-operatively. Recent studies explored the use of a reconstituted type I bovine collagen bioinductive implant derived from the bovine Achilles tendon to improve healing rates and tissue thickness, leading to favorable clinical outcomes. Therefore, we aimed to evaluate whether using this collagen implant to cover the lateral side of the sutured rotator cuff enhances the HLT size, formation, and maintenance at 6-8 weeks post-operatively. Methods: In this retrospective cohort study, we analyzed patients who underwent arthroscopic rotator cuff repair using the surface-holding method. Fifty-eight patients were treated without implants (H group), while 58 received bioinductive collagen implants (REGENETEN; Smith & Nephew, Andover, MA, USA) (R group). Magnetic resonance imaging was performed at 1 week and 6-8 weeks post-operatively to evaluate HLT thickness, classified as grades 1 (no HLT), 2 (HLT not exceeding the line connecting the cuff surface and the lateral edge of the greater tuberosity), or 3 (HLT exceeding the line). Retears at 6-8 weeks post-operatively were also assessed. Results: At 1 week post-operatively, 55.2% of the H group and 60.3% of the R group were classified as grade 3, with no significant difference ( Conclusion: Implanting a reconstituted type I bovine collagen bioinductive implant in arthroscopic rotator cuff repair using the surface-holding method helps to preserve and enhance HLT thickness, with a higher proportion of patients achieving grade 3 HLT at 6-8 weeks post-operatively. These findings suggest the potential of collagen implants to improve tendon-bone healing and structural outcomes.

Indexed as

Arthroscopic rotator cuff repairBioinductive implantBone marrow stimulationHematoma-like tissueRotator cuff tearSurface-holding technique

Identifiers

PMID42078589
PMCPMC13134019

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.