Evidence map›Paper›PMID 42078550›Full record

ArticleFrontiers in pediatrics2026

Comparative efficacy of quarterly vs. monthly triptorelin in Chinese girls with central precocious puberty: a 12-month observational study.

Hongyi Cai, Wenyong Wu, Xin Yuan, Ying Zhang, Xiaohong Yang, Xiaozhen Huang, Zhuanzhuan Ai, Dandan Li, Ruimin Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongyi CaiDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Wenyong WuDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Xin YuanDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Ying ZhangDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Xiaohong YangDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Xiaozhen HuangDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Zhuanzhuan AiDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Dandan LiDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.
Ruimin ChenDepartment of Endocrinology, Genetics, and Metabolic Diseases, Fuzhou First General Hospital Affilliated with Fujian Medical University, Fuzhou Children's Hospital, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to compare the clinical efficacy of quarterly (15 mg/90 days) versus monthly (3.75 mg/28 days) triptorelin formulations with respect to bone maturation, predicted adult height (PAH), and hormonal suppression in Chinese girls with central precocious puberty (CPP). Methods: This retrospective cohort study included 70 girls diagnosed with CPP at Fuzhou First General Hospital from March 2023 to 2025. Participants were assigned to either a quarterly regimen (triptorelin 15 mg every 90 days, Results: After 12 months of treatment, both regimens achieved effective and comparable suppression of LH (quarterly: 0.30 ± 0.19 IU/L; monthly: 0.30 ± 0.26 IU/L; both Conclusion: Quarterly triptorelin demonstrated efficacy comparable to that of monthly administration in suppressing puberty and improving PAH in Chinese girls with CPP.

Indexed as

bone agecentral precocious pubertylong-acting formulationpredicted adult heighttriptorelin

Identifiers

PMID42078550
PMCPMC13128640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.