ArticleFrontiers in pediatrics2026
Compassionate use of the Seraph® 100 affinity blood filter in pediatric refractory streptococcal septic shock: a case report.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Novel extracorporeal therapies in children.Pediatric nephrology (Berlin, Germany) · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: Septic shock remains a major cause of morbidity and mortality in pediatric intensive care units, particularly in refractory cases unresponsive to standard therapy. Invasive Case Presentation: We report the compassionate use of the Seraph® 100 Microbind® affinity blood filter in a previously healthy 7-year-old girl with refractory septic shock caused by invasive Conclusion: In this case, pathogen-binding hemoperfusion with the Seraph® 100 filter was technically feasible and temporally associated with hemodynamic and metabolic improvement in refractory pediatric septic shock. Although causality cannot be established, these findings suggest a potential role for hemoperfusion as an adjunctive rescue therapy in selected cases. Further prospective studies are needed to determine its safety, optimal timing, and clinical efficacy in pediatric populations.
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