Evidence map›Paper›PMID 42078531›Full record

ArticleFrontiers in microbiology2026

Developing

Yutong Ai, Kainan Song, Dongliang Xiao, Qun Yue, Chen Wang, Linan Xie, Liwen Zhang, Yuquan Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yutong Ai *National Key Laboratory of Agricultural Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Kainan Song *National Key Laboratory of Agricultural Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Dongliang XiaoCollege of Life and Health, Dalian University, Dalian, China.
Qun YueNational Key Laboratory of Agricultural Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Chen WangNational Key Laboratory of Agricultural Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Linan XieNational Key Laboratory of Agricultural Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Liwen ZhangNational Key Laboratory of Agricultural Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Yuquan XuNational Key Laboratory of Agricultural Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Beauvericin is a cyclodepsipeptide with insecticidal, antitumor, and antimicrobial activities, yet its application is limited by low yields. Filamentous fungi represent promising cell factories for complex natural products, but constraints in genetic manipulation and productivity hinder their widespread use. Methods: In this study, we developed a high-efficiency fungal cell factory for the Results: The engineered strain Discussion: This study achieves the highest beauvericin yield reported to date and establishes a generalizable platform for the heterologous production of diverse nonribosomal peptides (NRPs), with broad implications for sustainable biomanufacturing and natural product discovery.

Indexed as

beauvericincell factoryfilamentous fungusheterologous expressionnonribosomal peptide synthetase

Identifiers

PMID42078531
PMCPMC13128545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.