ArticleFrontiers in medicine2026
Impact of relaxation training and sedative medication use on respiratory recovery in hospitalized patients with respiratory diseases: a retrospective observational study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Psychological distress and sedative medication exposure are common among hospitalized patients with respiratory diseases and may influence clinical recovery. However, evidence regarding the combined impact of relaxation training and medication use on respiratory outcomes remains limited. This study aimed to examine the association between relaxation training, sedative or psychotropic medication use, and respiratory recovery in patients hospitalized with respiratory diseases. Methods: A retrospective observational study was conducted using electronic medical records from Hejiang County People's Hospital, Sichuan Province, China. Consecutive adults ( ≥ 18 years) admitted with a primary diagnosis of chronic obstructive pulmonary disease, pneumonia, asthma, bronchiectasis, or interstitial lung disease between January 2020 and January 2025 were included. Patients were categorized according to documented exposure to relaxation training during hospitalization. The primary outcome was respiratory recovery at discharge, defined a priori using objective criteria based on routinely documented records: successful discontinuation of invasive or non-invasive ventilatory support (if applicable), oxygen saturation ≥ 95% on room air for ≥ 4 h, respiratory rate 12-24 breaths/min at rest, and no evidence of ongoing respiratory failure (pH ≥ 7.35 and no worsening hypercapnia [PaCO Results: A total of 389 patients were included (mean age 63.3 ± 12.2 years; 58.1% male), of whom 158 (40.6%) received relaxation training. In multivariable analysis, younger age (OR = 0.96, 95% CI 0.94-0.98, Conclusion: In this retrospective cohort of hospitalized patients with respiratory diseases, engagement in relaxation training was independently associated with improved respiratory recovery, whereas early sedative medication exposure predicted poorer outcomes. Psychological and physiological parameters jointly influenced recovery probability. These findings underscore the importance of integrating psychological relaxation interventions and cautious sedative management in the clinical care of respiratory patients.
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