ReviewOncology reviews2026
New understanding of the molecular pathogenesis and therapeutic progress of hepatocellular carcinoma.
Review in Oncology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatocellular carcinoma (HCC) is a lethal malignancy with strong ties to chronic liver diseases and metabolic risks. Its pathogenesis involves complex biological processes where disrupted tumor suppressor genes and activated oncogenes drive aberrant signaling pathways and cellular differentiation. Since most patients are diagnosed at advanced stages, only a minority qualify for curative therapies. Although significant therapeutic advances have been made, the overall prognosis remains poor, largely due to high rates of recurrence and metastasis. Therefore, a deeper understanding of HCC's molecular mechanisms is crucial for developing effective targeted treatments. This review summarizes current insights into HCC pathogenesis and systematically elaborates on contemporary therapies, discussing their respective advantages and limitations.
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