ArticleCancer diagnosis & prognosis
Prognostic Nutritional Index Predicts Early Recurrence After Esophagectomy for Esophageal Cancer Following Neoadjuvant Chemotherapy.
Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/Aim: Although neoadjuvant chemotherapy (NAC) has improved oncologic outcomes in esophageal cancer, early postoperative recurrence remains a major cause of a poor prognosis. Immune-, inflammation-, and nutrition-based prognostic scores (IINBPS), such as the prognostic nutritional index (PNI), are reported prognostic markers in various malignancies; however, their ability to predict early recurrence after NAC remains unclear. This study aimed to identify the most reliable IINBPS for predicting early recurrence after esophagectomy following NAC. Patients and Methods: We retrospectively analyzed 61 patients with esophageal cancer who underwent curative esophagectomy following NAC between January 2012 and December 2024. Early recurrence was defined as recurrence within six months after surgery. Clinicopathological factors and IINBPS before and after NAC were evaluated. Receiver operating characteristic curve analysis was used to assess predictive performance, and risk factors for early recurrence were analyzed using univariate and multivariate logistic regression analyses. Results: Early postoperative recurrence occurred in 13 patients (21.3%). Among the evaluated IINBPS, pre-NAC PNI demonstrated the highest discriminatory ability, with an area under the receiver operating characteristic curve of 0.71. Patients with Conclusion: Pre-NAC PNI was the most useful IINBPS predictor of early recurrence after esophagectomy for esophageal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.