ArticleFrontiers in physiology2026
Remote stimulation of mitochondria and the antioxidant potential of thymocytes by weak non-ionizing non-thermal broadband pulsed electromagnetic fields in mouse.
Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Leading medical centers are currently considering pulsed electromagnetic therapy as a promising approach to prolong active life. Objective: The aim of this study was to investigate the effects of non-ionizing electromagnetic fields on mitochondrial activity and the state of the lipid peroxidation system, an antioxidant protection system in mice. Methodology: The studies were carried out on 60 BALB/c mice in accordance with bioethical standards and general ethical principles of animal experimentation. The animals were divided into 5 groups. The groups were placed in different rooms, standing at a considerable distance from each other. Experimental animals were exposed to non-invasive electromagnetic therapy device "TOR". The mitochondrial activity of thymocytes and the total antioxidant potential of the blood plasma were analyzed in all animals. Results: The study showed that weak non-ionizing non-thermal broadband pulsed electromagnetic fields (EMF) increased the antioxidant potential of mouse blood: at minimum exposure (1 min/h/10 nights) by almost 8% (p > 0.05), at maximum (5 min/h/10 nights) - by 20.6% (p< 0.05) - compared to the negative control group (young animals not exposed to EMF). The experiment confirms the dose-dependent stimulating effect of EMF on the mitochondria of thymocytes; at maximum exposure, the changes become statistically significant (increase in mitochondrial fluorescence by 29% compared to the negative control group, p< 0.05). Conclusion: The biological effects of non-ionizing electromagnetic fields are diverse. Due to their high penetrating power, they are able to affect deep-seated organs and tissues, thereby opening up new approaches in medicine and regenerative therapy that are cost-effective for patients and elicit cellular responses similar to physical exercise.
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