Evidence map›Paper›PMID 42078193›Full record

ArticleOpen forum infectious diseases2026

Adjunct Diagnostic Accuracy of Antigen-specific Interleukin-2 for Latent Tuberculosis Infection in Pregnancy.

Felix Bongomin, Phillip Ssekamatte, Ronald Olum, Diana Sitenda, Davis Kibirige, Joseph Baruch Baluku, Stephen Cose, Irene Andia-Biraro

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felix BongominDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.ORCID https://orcid.org/0000-0003-4515-8517
Phillip SsekamatteDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.ORCID https://orcid.org/0000-0002-3418-8414
Ronald OlumDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-1289-0111
Diana SitendaClinical Research Unit, Tuberculosis and Comorbidity Consortium, Kampala, Uganda.ORCID https://orcid.org/0000-0001-8169-2819
Davis KibirigeClinical Research Unit, Tuberculosis and Comorbidity Consortium, Kampala, Uganda.ORCID https://orcid.org/0000-0001-5127-3031
Joseph Baruch BalukuMakerere University Lung Institute, Kampala, Uganda.ORCID https://orcid.org/0000-0002-5852-9674
Stephen CoseMedical Research Council/Uganda Virus Research Institute (MRC/UVRI) and London School of Hygiene & Tropical Medicine (LSHTM) Uganda Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0002-5156-037X
Irene Andia-BiraroClinical Research Unit, Tuberculosis and Comorbidity Consortium, Kampala, Uganda.ORCID https://orcid.org/0000-0002-8303-6046

Funding

Minnesota-Makerere-Mbarara Neuro-Infectious Disease Research Training ConsortiumD43TW012266 · FIC · UNIVERSITY OF MINNESOTA · PI David R Boulware, David Bisagaya Meya · 2024 to 2026
$747k
FIC NIH HHS D43 TW012266
6 · The paper itself

Abstract

Background: Pregnancy modulates immune responses against Methods: We enrolled pregnant women without previous active TB at Kawempe National Referral Hospital, Uganda, in 2020. We tested for LTBI using the QuantiFERON-TB Gold-Plus assay. Blood in quantiFERON blood collection tubes was stimulated with Results: Of 159 participants, the median gestational age was 26.1 (IQR: 20.0-31.6) weeks, 8.2% (n = 13) had HIV, and 10.1% (n = 16) were recent TB contacts. Overall, 79 (49.7%) had LTBI. Conclusions:

Indexed as

diagnostic biomarkerinterleukin-2latent tuberculosis infectionpregnant women

Identifiers

PMID42078193
PMCPMC13132169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.