Evidence map›Paper›PMID 42078109›Full record

ArticleThe Pan African medical journal2025

Isolated splenic sarcoidosis: an unexpected cause for splenomegaly (a case report).

Christoffel Roche McDuling, Ellie Georgiou, Carina Labuschagne

Abstract readCase Reports
In one paragraph

Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christoffel Roche McDulingPaarl Provincial Hospital, 10 Hospital Street, Lemoenkloof, Western Cape, South Africa.
Ellie GeorgiouPaarl Provincial Hospital, 10 Hospital Street, Lemoenkloof, Western Cape, South Africa.
Carina LabuschagneDepartment of Pathology, National Health Laboratory Service, University of Stellenbosch, Tygerberg Hospital, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcoidosis is an idiopathic disease characterised by non-caseating granulomas affecting all organ systems. Sarcoidosis most commonly affects the lungs in >90% of cases but can present with extra-pulmonary manifestations; however, isolated splenic sarcoidosis is extremely uncommon. Isolated splenic sarcoidosis proves to be even more rare in a region where tuberculosis is endemic and presents with similar clinical manifestations, which makes diagnosis more challenging. This report describes the case of a young female presenting with non-specific abdominal complaints and clinical splenomegaly with unknown cause, and how the patient was worked up and the challenges that were faced in the diagnostic and therapeutic journey. The value of laparoscopic splenectomy is demonstrated, and the need for a combination of clinical, biochemical, radiological and histological modalities.

Indexed as

SarcoidosisSplenectomySplenic DiseasesSplenomegalyAdultFemaleHumansLaparoscopyacute care surgerycase reportsarcoidosissplenomegalyTuberculosis

Identifiers

PMID42078109
PMCPMC13134936

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.