ArticleInternational archives of otorhinolaryngology2026
Hearing Characteristics of Adults before Exposure to Potentially Ototoxic Chemotherapy.
Article in International archives of otorhinolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Cancer patients undergoing potentially-ototoxic chemotherapy may present a series of hearing disorders and risk factors prior to treatment. Thus, it is necessary to know the profile of these patients to promote preventive actions and guidelines regarding the hearing health of these individuals. Objective: To describe and relate the hearing characteristics of patients entering a chemotherapy service before the exposure to potentially-ototoxic drugs. Methods: We conducted a cross-sectional study of 261 individuals who started chemotherapy between April and December 2022. All patients filled out a hearing case history and underwent otoscopy. Individuals who had a non-altered otoscopy due to obstructive cerumen underwent distortion-product otoacoustic emissions (DPOAEs) at 2, 4, 6, 8, 10, and 12 kHz in both ears. Results: In total, 83% of the patients reported good hearing and 31% described some level of hearing impairment. The most prevalent self-reported hearing issue was tinnitus (35%). Only 12% had a medical diagnosis of hearing loss, and 20% had obstructive cerumen during otoscopy. Individuals who reported hearing impairments such as reduced hearing and difficulty understanding noises demonstrated fewer responses in the DPOAEs at various frequencies. In addition, there were significant differences in DPOAE amplitudes among different age groups. Given the substantial burden of hearing loss with ageing, attention to this population is essential for the possibility of preventing or delaying hearing loss. Conclusion: Cancer patients entering a chemotherapy service have a hearing case history of risk factors and hearing alterations prior to exposure to potentially-ototoxic drugs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.