Evidence map›Paper›PMID 42077849›Full record

ArticleACS omega2026

Peptide Design for Targeting BTB Domain Homodimerization of BACH2: Complementary

Efe Acar, Hüveyda Başağa, Emel Timuçin, Ahmet Can Timuçin

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Efe AcarDepartment of Molecular Biology and Genetics, Graduate School of Natural and Applied Sciences, Acibadem Mehmet Ali Aydinlar University, İstanbul 34752, Türkiye.
Hüveyda BaşağaDepartment of Molecular Biology, Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Sabancı University, İstanbul 34956, Türkiye.
Emel TimuçinDepartment of Molecular Biology and Genetics, Faculty of Science, Gebze Technical University, Kocaeli 41400, Türkiye.ORCID https://orcid.org/0000-0003-0048-0668
Ahmet Can TimuçinDepartment of Molecular Biology and Genetics, Graduate School of Natural and Applied Sciences, Acibadem Mehmet Ali Aydinlar University, İstanbul 34752, Türkiye.ORCID https://orcid.org/0000-0002-9483-3593

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Potential activation of NRF2 via targeting its nuclear suppressor BACH2 represents an unexplored field, forming a gap yet to be addressed. Besides, considering the pathological role of BACH2 in tumor immunosuppression, an attempt to target this repressor was deemed necessary. Despite this background, a peptide-based modulator that could interfere with the BACH2 BTB domain has not been reported. Accordingly, using

Identifiers

PMID42077849
PMCPMC13129818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.