ArticleAquaculture nutrition2026
Dietary Supplementation With CoQ10 and Sel-Plex Mitigates the Effects of Elevated Water Temperature on Performance, Digestive Physiology, Immune Competence, and Antioxidant Balance in Rainbow Trout.
Article in Aquaculture nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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5 authors.
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Abstract
Background/Aims: Elevated water temperatures can impair fish growth, immunity, and physiological performance. This study aimed to evaluate the effects of dietary coenzyme Q10 (CoQ10) and organic selenium (O-Se; Sel-Plex) supplementation on growth, digestive enzymes, innate immunity, antioxidant capacity, and the expression of stress- and immune-related genes ( Methods: A total of 225 rainbow trout (21 ± 0.5 g) were stocked in 150-L recirculating tanks at either optimal (15°C) or elevated (20°C) water temperatures. Fish were fed diets supplemented with CoQ10 (0 or 20 mg/kg) and/or Sel-Plex (0 or 5 mg/kg) for 60 days. Growth indices, digestive enzyme activity, hepatic antioxidant capacity, immune parameters, and the expression of Results: Elevated temperature significantly reduced growth, feed efficiency, and immune status. Dietary supplementation with CoQ10 or O-Se improved hepatic antioxidant capacity, digestive enzyme activity, and innate immunity, with the greatest effects observed when both supplements were combined. Cosupplementation also mitigated heat-induced upregulation of HSP70-α and IL-1β and reduced liver malondialdehyde (MDA) levels. Conclusion: Combined dietary CoQ10 and O-Se supplementation alleviate the adverse effects of elevated water temperatures on rainbow trout by enhancing growth, physiological performance, antioxidant defenses, and immune responses.
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