ArticleCase reports in ophthalmology
Acetazolamide-Induced Bilateral Uveal Effusions and Secondary Angle Closure: A Case Report.
Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Introduction: Acetazolamide-induced uveal effusion and secondary angle closure is a rarely reported but clinically significant phenomenon. The reaction is idiosyncratic and independent of dosage or prior exposure. Case Presentation: A 52-year-old patient developed severe bilateral uveal effusions, acute angle closure, and myopic shift 24 h after commencing acetazolamide for altitude sickness prophylaxis. The case demonstrates unusually severe posterior involvement after a single prophylactic dose, with dramatic recovery following initiation of intravenous methylprednisolone. Conclusion: Given the widespread use of acetazolamide in ophthalmology and other medical disciplines, clinicians must be aware of potentially sight-threatening drug reactions. Prescription of acetazolamide for altitude sickness prophylaxis represents a unique risk, as patients are likely to be travelling to remote destinations. First-time dosing should occur where urgent medical assessment is readily accessible.
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