ArticleCureus2026
Inflammatory Biomarker Profiles in Odontogenic Infections: Evaluation of C-reactive Protein (CRP), Procalcitonin, WBC Count, and Neutrophil-to-Lymphocyte Ratio.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Comparative assessment of total WBC and C-reactive protein counts to procalcitonin levels in subjects having maxillofacial space infection.Bioinformation · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOdontogenic infections range from localized abscesses to severe, life-threatening conditions involving deep fascial spaces and systemic complications. Early identification of disease severity is essential for appropriate management and prevention of adverse outcomes. Inflammatory biomarkers, such as C-reactive protein (CRP), procalcitonin (PCT), white blood cell (WBC) count, and neutrophil-to-lymphocyte ratio (NLR), provide objective indicators of systemic infection and may aid in prognostic assessment. This study aimed to evaluate the levels of CRP, PCT, WBC count, and NLR in patients with odontogenic infections and determine their association with disease severity and clinical outcomes. MATERIALS AND
methodsThis prospective cohort study included 50 patients with odontogenic infections who were admitted to the Jawahar Medical Foundation's AC Patil Memorial (ACPM) Dental College, Dhule, India, between January and December 2023. Severity was classified into four groups using a structured scoring system. Blood samples were collected upon admission to determine CRP, PCT, WBC count, and NLR levels. Statistical analysis was performed using the Kruskal-Wallis test, Spearman correlation, Mann-Whitney U test, regression analysis, and receiver operating characteristic (ROC) curve analysis.
resultsThe mean age was 38.5 ± 14.2 years, with a male predominance. Median CRP was 72 mg/L, PCT 0.38 ng/mL, mean WBC 12.8 ± 3.8 ×10
conclusionInflammatory biomarkers, particularly PCT and NLR, are reliable indicators of disease severity and predictors of clinical outcomes in odontogenic infections, supporting their use in early risk stratification and management.
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