Evidence map›Paper›PMID 42077693›Full record

ArticleCureus2026

Racing Heart Under Stormy Skies: A Journey From Agranulocytosis to Thyroid Storm.

Jia Miao Tan, Mark Vin Wong, Dorothy Maria Anthony Bernard, Siew Hui Foo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jia Miao TanEndocrine Unit, Hospital Selayang, Selayang, MYS.
Mark Vin WongInternal Medicine, Hospital Selayang, Selayang, MYS.
Dorothy Maria Anthony BernardEndocrinology, Hospital Selayang, Selayang, MYS.
Siew Hui FooMedicine, Subang Jaya Medical Centre, Subang Jaya, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid storm is a rare, severe, and life-threatening exacerbation of thyrotoxicosis, characterized by dysfunction of the thermoregulatory, central nervous, gastrointestinal, hepatic, and cardiovascular systems. We present a 31-year-old female with newly diagnosed Graves' disease complicated by carbimazole-induced agranulocytosis. The delay in initiating adjunctive therapy to control the thyrotoxicosis due to suspected sepsis was followed by rapid development of thyroid storm requiring therapeutic plasma exchange (TPE) and urgent thyroidectomy. This case highlights the importance of prompt recognition and of distinguishing thyroid storm from sepsis in the setting of anti-thyroid drug-induced agranulocytosis and underscores TPE as an effective, well-tolerated bridging therapy for thyroid storm before definitive treatment.

Indexed as

agranulocytosisanti-thyroid drugplasma exchangethyroidectomythyroid storm

Identifiers

PMID42077693
PMCPMC13130835

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.