ArticleEFSA journal. European Food Safety Authority2010
Scientific Opinion on Risk of transmission of TSEs via semen and embryo transfer in small ruminants (sheep and goats).
Article in EFSA journal. European Food Safety Authority, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Assessing the aggregated probability of entry of a novel prion disease agent into the United Kingdom.Microbial risk analysis · 2020Article
- Scientific Opinion on Risk of transmission of TSEs via semen and embryo transfer in small ruminants (sheep and goats).EFSA journal. European Food Safety Authority · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An assessment of the risk of transmission of Transmissible Spongiform Encephalopathies (TSEs) via semen and embryo transfer in small ruminants (sheep and goats) was performed. The TSE agents considered were Classical scrapie, Atypical scrapie and Bovine Spongiform Encephalopathy (BSE). Because of the lack of specific data for goats the assessment was carried out mainly using data obtained in sheep and, because of the similarities of TSE pathogenesis between sheep and goats, the assessment was also considered to be valid in goats. According to the data currently available, the risk of TSE transmission associated with semen and embryos collected from Classical Scrapie incubating sheep and goats ranges from negligible to low but the data are insufficient to conclude that such a risk is negligible. Because of the similarities between Classical scrapie and BSE pathogenesis in small ruminants, this statement is also to be considered valid for BSE. The lack of knowledge of the pathogenesis and anatomical distribution of the Atypical scrapie agent within affected animals hampers the possibility to provide an assessment of its transmission risk via semen or embryos. Due to the use of animal-derived hormones and surgical devices for artificial insemination and embryo transfer procedures there is an inherent but unquantifiable risk of iatrogenic TSE transmission associated with these practices.
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Registered trials
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