ArticleAsian biomedicine : research, reviews and news2026
The association of clinical characteristics and liver stiffness measurement with liver viscosity measured by shear wave elastography in patient with non-alcoholic fatty liver disease.
Article in Asian biomedicine : research, reviews and news, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Viscosity plane-wave ultrasound (Vi.PLUS) measures tissue viscosity by using shear wave dispersion within tissues. The tissue viscosity is associated with the degree of liver necroinflammation, which is an important mechanism that leads to the development of liver fibrosis (LF). Objectives: This study aimed to examine the association of clinical characteristics and liver stiffness measurement (LSM) by magnetic resonance elastography (MRE) with liver viscosity measurement by shear wave elastography (SWE) in patients with non-alcoholic fatty liver disease. Methods: This monocentric cross-sectional study with retrospective data collection included 164 patients. The medical records of patients aged ≥18 years with non-alcoholic fatty liver disease (NAFLD) and who underwent MRE and Vi.PLUS at King Chulalongkorn Memorial Hospital were reviewed. The viscosity measurements were performed according to guidelines. Results: Of the 164 patients, 11 (6.7%) had invalid or unreliable measurements by elastographic technique and 4 (2.4%) were excluded due to incomplete clinical data. This resulted in 149 subjects being included in the final analysis. The study found good correlation between viscosity measurements by shear wave elastography and LSM by MRE ( Conclusion: In conclusion, viscosity measured by shear wave elastography is a non-invasive method of assessing liver inflammation with good correlation to LF. This may aid the early diagnosis of liver inflammation in patients with NAFLD.
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