ArticleAnnals of thoracic medicine
Correlation between the severity of asthma and computed tomography-based large airway structural changes among children under 3 years of age.
Article in Annals of thoracic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe absence of objective and quantitative criteria of pediatric asthma is a persistent barrier in the early diagnosis and assessment of severity. Alterations in major airway structures in individuals with asthma may indicate the severity of the disease. This study was conducted to determine the correlation between the morphologic characteristics of the respiratory tract with the degrees of the severity of asthma among the children under 3 years old.
methodsA retrospective analysis of low-dose computed tomography (CT) data was performed to determine the potential predictive value of morphologic characteristics of big airways in determining the response to pharmacologic treatment in children with asthma <3 years of age. The analysis was performed using a machine learning approach.
resultsTwo hundred and forty-four children with asthma were diagnosed with moderate (
conclusionThe morphologic characteristics of the respiratory tract are closely related to the degrees of the severity of asthma among the children under 3 years old.
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