Evidence map›Paper›PMID 42076707›Full record

ArticleVeterinary sciences2026

Clinical Value of Serum Cardiac Troponin I, Trimethylamine N-Oxide (TMAO), and Galectin-3 in Canine Myxomatous Mitral Valve Degeneration: A Preliminary Study.

Alessandra Gavazza, Andrea Maggiori, Lucia Biagini, Alessandro Fruganti, Oriol Domenech, Dalida Arletti, Maria Chiara Muollo, Chiara Masci, Giacomo Rossi

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandra GavazzaSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.ORCID 0000-0002-2070-8028
Andrea MaggioriSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.
Lucia BiaginiSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.ORCID 0000-0001-5990-1514
Alessandro FrugantiSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.
Oriol DomenechDepartment of Cardiology, Anicura Istituto Veterinario di Novara, Strada Provinciale 9, 28060 Granozzo con Monticello, NO, Italy.
Dalida ArlettiSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.
Maria Chiara MuolloSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.ORCID 0009-0005-7723-5822
Chiara MasciSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.ORCID 0009-0009-8641-5541
Giacomo RossiSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, MC, Italy.ORCID 0000-0001-8617-5984

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myxomatous mitral valve disease (MMVD) is a common cardiac disorder in older small- to medium-sized dogs. Diagnosis and staging are primarily based on echocardiography; however, circulating cardiac biomarkers have gained increasing interest because they are rapid and easily measurable. In this context, the investigators' aim was to study the clinical value of galectin-3 (Gal-3) and trimethylamine N-oxide (TMAO), in dogs affected by MMVD, in comparison to cardiac troponin I (cTnI), a well-established biomarker of myocardial injury, and echocardiography. Twenty-two dogs were classified as healthy controls or affected by MMVD and staged according to American College of Veterinary Internal Medicine (ACVIM) guidelines. Serum concentrations of Gal-3, TMAO, and cTnI were measured and compared among groups. No significant differences in serum Gal-3 concentration were detected among groups (

Indexed as

cardiac biomarkerscardiac troponin Idogechocardiographygalectin-3microbiotamyxomatous mitral valve diseasetrimethylamine N-oxide

Identifiers

PMID42076707
PMCPMC13120253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.