Evidence map›Paper›PMID 42076684›Full record

ReviewVeterinary sciences2026

Mechanism of Action of Plant Extracts in Preventing Post-Weaning Diarrhea in Piglets: A Review.

Xiaohan Jiang, Haibo Xiao, Peng Huang

Abstract readReview
In one paragraph

Review in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaohan JiangHunan Key Laboratory of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Hunan Agricultural University, Changsha 410127, China.
Haibo XiaoCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410127, China.
Peng HuangHunan Key Laboratory of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Hunan Agricultural University, Changsha 410127, China.ORCID 0000-0002-8367-8196

Funding

This research was supported by National Key R&D Program of China 2023YFD1301200
6 · The paper itself

Abstract

Post-weaning diarrhea (PWD) in piglets is a common multifactorial disease in global swine production. Traditional prevention and control strategies relying on high-dose zinc oxide and antibiotics face limitations due to antimicrobial resistance and environmental concerns. This review systematically elucidates the mechanisms of action of plant extracts as alternative interventions against PWD, focusing primarily on categories such as polysaccharides, polyphenols, essential oils, and alkaloids. This review discusses how plant extracts exert their effects through various mechanisms, including improving feed intake, enhancing antioxidant and immune capacities, modulating gut microbiota, repairing intestinal barrier function, and inhibiting pathogens-to alleviate diarrhea induced by weaning stress and pathogenic infections. The findings indicate that plant extracts offer advantages such as multi-target effects, natural origin, and a low propensity for inducing resistance, highlighting their promising potential as alternatives to conventional additives. However, challenges related to compositional complexity, stability, and bioavailability require further investigation and optimization.

Indexed as

gut microbiotaintestinal barrieroxidative stressplant extractspost-weaning diarrhea

Identifiers

PMID42076684
PMCPMC13119882

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.