ArticleSensors (Basel, Switzerland)2026
Multimodal PPG-Based Arrhythmia Detection Using a CLIP-Initialized Multi-Task U-Net and LLM-Assisted Reporting.
Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Photoplethysmography (PPG) has emerged as an attractive modality for non-invasive cardiovascular monitoring due to its low cost, unobtrusive nature, and ubiquity in consumer wearable devices. Despite its potential, existing PPG-based arrhythmia detection systems remain limited in scope: (i) most target only atrial fibrillation, (ii) temporal localization of abnormal segments is rarely provided, and (iii) deep learning models lack explainability, hindering adoption in clinical workflows. We present a comprehensive and fully integrated framework for multi-class arrhythmia detection, segmentation, and explainability based on PPG waveforms, Heart Rate Variability (HRV), and structured clinical metadata. The proposed system introduces a CLIP-style contrastive learning module aligning PPG waveforms with clinical variables and rhythm-state textual descriptions using BioBERT; a multitask U-Net architecture performing 4-class classification and 1D segmentation; a Retrieval-Augmented Generation (RAG) pipeline leveraging Gemini Flash large language models to produce guideline-grounded diagnostic reports; and a real-time Streamlit-based web platform supporting inference, visualization, and database storage. The system significantly improves classification accuracy (from 86.27% to 91.19%) and segmentation Dice (from 0.5815 to 0.7167). These results demonstrate the feasibility of a robust, multimodal, and explainable PPG-based arrhythmia monitoring system for real-world applications.
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