Evidence map›Paper›PMID 42076067›Full record

ArticlePharmaceutics2026

Differential Modulation of JAK/STAT3 Signaling and BCL-2 Family Proteins by Tetracycline Analogues in Leukemia Models.

Zienab M Hassan, Doste R Mamand, Hoda W El-Gawly, Nagla A El-Sherbeeny, Hala M F Mohammad, Mohamed K Elkherbetawy, Oscar P B Wiklander, Moustapha Hassan

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zienab M HassanDepartment of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0009-0005-6855-9622
Doste R MamandDepartment of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0002-4785-0796
Hoda W El-GawlyDepartment of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.
Nagla A El-SherbeenyDepartment of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-7688-408X
Hala M F MohammadDepartment of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-1349-5300
Mohamed K ElkherbetawyDepartment of Pathology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-5716-8459
Oscar P B WiklanderDepartment of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0003-1176-8114
Moustapha HassanExperimental Cancer Medicine, Division of Biomolecular and Cellular Medicine (BCM), Department of Laboratory Medicine, Karolinska Institutet, 141 86 Huddinge, Sweden.ORCID 0000-0003-1927-5859

Funding

Center for Innovative Medicine (CIMED) junior investigator grants (FoUI-976434)Karolinska Institutet (2-116/2023)Ministry of Higher Education of the Arab Republic of Egypt scholarship (JS15/19)Radium Hemmets Research Funds (Project #241392)Swedish Cancer Society (Cancerfonden, 23 2935 Pj)Swedish Research Council (VR, 2022-02449)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

doxycycline (DOX) and minocycline (MIN)JAK2/STAT3leukemiatetracycline-3 (COL-3)

Identifiers

PMID42076067
PMCPMC13118528

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.