Evidence map›Paper›PMID 42075952›Full record

ReviewMolecules (Basel, Switzerland)2026

Chitosan Derivatives: Challenges and Opportunities in the Green and Sustainable Transition Era.

Ana Morais, Rita Lima, Madalena M M Pinto, Maria Elizabeth Tiritan, Carla Fernandes

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana MoraisLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0009-0007-6240-3701
Rita LimaLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0001-5222-6077
Madalena M M PintoLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-4676-1409
Maria Elizabeth TiritanLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0003-3320-730X
Carla FernandesLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0003-0940-9163

Funding

Fundação para a Ciência e Tecnologia UID/04423/2025, UID/PRR/04423/2025, LA/P/0101/2020
6 · The paper itself

Abstract

Transition towards sustainable and environmentally friendly practices within the field of chemistry and materials science has become essential in light of current environmental challenges. This review provides a comprehensive overview of the challenges and opportunities in the various steps involved in producing chitosan derivatives, with particular emphasis on eco-friendly strategies. Key methodologies for chitin isolation from diverse natural sources, chitin deacetylation, and the chemical modification of chitosan are discussed, integrating green chemistry principles and eco-efficient processes. Advances in sustainable technologies that prioritize cost-effectiveness, safety, and performance are highlighted. The importance of interdisciplinary collaboration, innovative isolation and purification strategies, the adoption of continuous-flow processes, and greener synthetic approaches, such as click chemistry, are also explored. Overall, this work supports the adoption of a holistic approach for the development of chitosan derivatives, contributing to more sustainable and environmentally responsible materials and production processes.

Indexed as

chitinchitosanchitosan derivativesclick chemistryeco-friendlygreen chemistrysustainable chemistry

Identifiers

PMID42075952
PMCPMC13118836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.