ArticleMolecules (Basel, Switzerland)2026
Effect of Phthalocyanines Substitution Pattern on Their Loading into Bacterial Cellulose Nanocrystals.
Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Photodynamic therapy (PDT) has already gained immense attention in the anti-tumor field due to its low toxicity and non-invasiveness compared to traditional treatment methods. Therefore, the development of efficient photosensitizers is crucial for the advancement of photodynamic therapy. Although phthalocyanines (Pcs) have attracted huge attention as efficient photosensitizers, their clinical applications are hindered by poor solubility and a tendency to aggregate. Herein, two different Pcs that have different polarities were loaded into bacterial cellulose nanoparticles via non-covalent interactions. The aggregation behaviors and singlet oxygen production efficiencies were studied, as well as the influence of the Pc polarity on loading ratios. It was observed that octa-propylsulfonyl phthalocyanine ZnPc(SO
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