Evidence map›Paper›PMID 42075900›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Comparative Pharmacological Profiling of Psychotherapeutic Drugs Reveals a Functional Taxonomy Based on Direct Inhibition of Smooth Muscle Excitability.

María Jesús Castrillejo, Alfonso Velasco, Juan F Mielgo-Ayuso, Jesús Pérez, Manuel Garrosa, Carlos Alberto Rodríguez-Arias, Diego Fernández-Lázaro

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Jesús CastrillejoDepartment of Cell Biology, Genetics, Histology and Pharmacology, Faculty of Medicine, University of Valladolid, 47005 Valladolid, Spain.ORCID 0009-0004-5075-7658
Alfonso VelascoDepartment of Cell Biology, Genetics, Histology and Pharmacology, Faculty of Medicine, Institute of Neurosciences of Castile and Leon (INCYL), University of Valladolid, 47005 Valladolid, Spain.
Juan F Mielgo-AyusoFaculty of Health Sciences, University of Burgos (UBU), 09001 Burgos, Spain.ORCID 0000-0002-6554-4602
Jesús PérezDepartment of Medicine, Faculty of Medicine, Institute of Biomedical Research (IBSAL), University of Salamanca, 37007 Salamanca, Spain.
Manuel GarrosaDegeneration and Regeneration Laboratory, Institute of Neurosciences of Castile and Leon (INCYL), University of Valladolid, 47005 Valladolid, Spain.ORCID 0000-0002-4280-5611
Carlos Alberto Rodríguez-AriasDegeneration and Regeneration Laboratory, Institute of Neurosciences of Castile and Leon (INCYL), University of Valladolid, 47005 Valladolid, Spain.
Diego Fernández-LázaroNeurobiology Research Group, University of Valladolid, 47005 Valladolid, Spain.ORCID 0000-0002-6522-8896

Funding

Consejería de Educación de la Junta de Castilla y León PID2022-141358OBI00
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autonomic side-effect liabilityex vivo assayfunctional pharmacological profilingK+-induced depolarizationpsychotherapeutic drugssmooth muscle excitability

Identifiers

PMID42075900
PMCPMC13118299

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.