Evidence map›Paper›PMID 42075794›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Kinetoplast-Directed Therapies: A Selective Mitochondrial Approach to Combat Leishmaniasis.

Jenny A Botero-Buitrago, Juan Camilo Cardozo-Muñoz, David Cisneros, Javier Santamaría-Aguirre, Koraima Torres, Socorro Espuelas, Javier Carrión, Christophe Dardonville

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jenny A Botero-BuitragoInstitute of Medicinal Chemistry, IQM-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0001-9990-4648
Juan Camilo Cardozo-MuñozInstitute of Medicinal Chemistry, IQM-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0003-1339-6377
David CisnerosInstitute of Medicinal Chemistry, IQM-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.
Javier Santamaría-AguirreResearch Group on Biodiversity, Zoonoses and Public Health (GIBCIZ), Research Institute on Zoonoses (CIZ), Faculty of Chemical Sciences (FCQ), Central University of Ecuador, Quito 170521, Ecuador.ORCID 0000-0002-1683-5737
Koraima TorresResearch Group on Biodiversity, Zoonoses and Public Health (GIBCIZ), Research Institute on Zoonoses (CIZ), Faculty of Chemical Sciences (FCQ), Central University of Ecuador, Quito 170521, Ecuador.
Socorro EspuelasDepartment of Pharmaceutical Sciences, School of Pharmacy and Nutrition, University of Navarra, 31009 Pamplona, Spain.
Javier CarriónICPVet Research Group, Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-7486-4942
Christophe DardonvilleInstitute of Medicinal Chemistry, IQM-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0001-5395-1932

Funding

Agencia Estatal de Investigación (MCIN/AEI/10.13039/501100011033) (Co-funded by European Regional Development Fund. ERDF, "A way to build Europe", by the European Union) PID2022-136438OB-I00Agencia Estatal de Investigación (MCIN/AEI/10.13039/501100011033) (Co-funded by European Regional Development Fund. ERDF, "A way to build Europe", by the European Union) PID2023-148406OB-I00
6 · The paper itself

Abstract

The leishmaniases are a group of neglected tropical diseases caused by kinetoplastid protozoa of the genus

Indexed as

DNA minor groove binderG-quadruplexkDNAkinetoplastleishmaniasismitochondrion-targetednanomedicinenanoparticletargeted drug deliverytopoisomerase

Identifiers

PMID42075794
PMCPMC13118928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.