Evidence map›Paper›PMID 42075756›Full record

ArticlePathogens (Basel, Switzerland)2026

Dysregulated IL-7/IL-7R-CD132 Axis and Intestinal Microsporidiosis in Crohn's Disease.

Carolina Hurtado-Marcos, Fernando Izquierdo, Soledad Fenoy, Carmen Del Águila, Jaume Pérez-Griera, Salvador Benlloch, Cirilo Amorós, Carlos García Ballesteros, Francisca López Chuliá, Juan Carlos Andreu-Ballester and 1 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carolina Hurtado-MarcosUniversidad CEU San Pablo, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0003-0364-7742
Fernando IzquierdoUniversidad CEU San Pablo, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0003-0367-007X
Soledad FenoyUniversidad CEU San Pablo, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0002-5218-6308
Carmen Del ÁguilaUniversidad CEU San Pablo, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain.ORCID 0000-0003-0063-7899
Jaume Pérez-GrieraLaboratory Department, University Clinical Hospital, 46010 Valencia, Spain.ORCID 0000-0001-7304-6227
Salvador BenllochDigestive Departament, Arnau de Vilanova Hospital, 46015 Valencia, Spain.ORCID 0000-0002-0794-6937
Cirilo AmorósDigestive Departament, Arnau de Vilanova Hospital, 46015 Valencia, Spain.
Carlos García BallesterosHematology Departament, Arnau de Vilanova Hospital, 46015 Valencia, Spain.
Francisca López ChuliáHematology Departament, Arnau de Vilanova Hospital, 46015 Valencia, Spain.
Juan Carlos Andreu-BallesterFoundation for the Promotion of Health and Biomedical Research in the Valencian Region, 46020 Benimaclet, Spain.ORCID 0000-0003-3790-3054
Carmen CuéllarDepartment of Microbiology and Parasitology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-7948-9889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease (CD) is frequently accompanied by T-cell lymphopenia and impaired mucosal immunity, conditions that may predispose to intestinal microsporidiosis by

Indexed as

Crohn DiseaseInterleukin-7Receptors, Interleukin-7AdultAntibodies, FungalApoptosisCase-Control StudiesCaspase 3FemaleHumansInterleukin-7 Receptor alpha SubunitMaleMiddle AgedProspective StudiesSignal TransductionYoung AdultAntibodies, FungalCaspase 3IL7 protein, humanIL7R protein, humanInterleukin-7Interleukin-7 Receptor alpha SubunitReceptors, Interleukin-7apoptosisbiomarkerscaspase-3CD132CD56+ lymphocytesCrohn’s diseaseEncephalitozoon cuniculimucosal immunitysurgical outcomesγδ T cells

Identifiers

PMID42075756
PMCPMC13118896

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.