Evidence map›Paper›PMID 42075665›Full record

ReviewMedicina (Kaunas, Lithuania)2026

The Overlap Between Crohn's Disease and Intestinal Tuberculosis: A Never-Ending Story.

Sergiu Marian Cazacu, Costin Teodor Streba, Cristian Constantin, Claudiu Marinel Ionele, Ion Rogoveanu, Alexandru Valentin Popescu, Mirela-Marinela Florescu

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Global burden of inflammatory bowel disease in Asia, 1990-2023: A global burden of disease study 2023.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sergiu Marian CazacuGastroenterology Department, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.ORCID 0000-0001-9623-7683
Costin Teodor StrebaClinical Emergency Hospital Craiova, 200642 Craiova, Romania.
Cristian ConstantinClinical Emergency Hospital Craiova, 200642 Craiova, Romania.
Claudiu Marinel IoneleGastroenterology Department, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.ORCID 0000-0001-5675-1741
Ion RogoveanuGastroenterology Department, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.
Alexandru Valentin PopescuDoctoral School, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.
Mirela-Marinela FlorescuClinical Emergency Hospital Craiova, 200642 Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of Crohn's disease has increased over the last few decades, even in developing countries, whereas that of intestinal tuberculosis has decreased, which places both diseases at an epidemiological crossroads. Crohn's disease and intestinal tuberculosis share many clinical, endoscopic, imaging, and pathological features, which sometimes make differential diagnosis very difficult; an accurate diagnosis is, however, very important since an erroneous treatment can worsen the evolution or delay proper therapy. The association between past TB infection and Crohn's disease can make the diagnosis especially hard. This review summarizes current data on specific features that allow differentiation between Crohn's disease and intestinal tuberculosis, paying particular attention to the microbiome, clinical signs, endoscopy, cross-sectional imaging, bacteriological, and immunological findings detailed. The importance of computerized models and scores for the differentiation is also detailed, because common features may make the differentiation based on a single criterion difficult.

Indexed as

Crohn DiseaseTuberculosis, GastrointestinalDiagnosis, DifferentialHumansCrohn’s diseasegranulomaintestinal tuberculosis

Identifiers

PMID42075665
PMCPMC13117682

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.