Virus-Mediated System for Simultaneous Gene Silencing and Genome Editing in Cotton.

Yufeng Zheng, Lianjia Zhao, Yulin Tian, Jiahao Lin, Xiaodong Liu, Jianfeng Lei

Abstract read

In one paragraph

Article in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

6 authors.

Yufeng ZhengInnovation Research Center for Efficient Genome Editing Technology and Precision Breeding Applications, College of Life Sciences, Xinjiang Agricultural University, Urumqi 830052, China.

Lianjia ZhaoInstitute of Crop Research, Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.

Yulin TianInnovation Research Center for Efficient Genome Editing Technology and Precision Breeding Applications, College of Life Sciences, Xinjiang Agricultural University, Urumqi 830052, China.

Jiahao LinResearch Center of Cotton Engineering, College of Agronomy, Xinjiang Agricultural University, Ministry of Education, Urumqi 830052, China.

Xiaodong LiuInnovation Research Center for Efficient Genome Editing Technology and Precision Breeding Applications, College of Life Sciences, Xinjiang Agricultural University, Urumqi 830052, China.

Jianfeng LeiResearch Center of Cotton Engineering, College of Agronomy, Xinjiang Agricultural University, Ministry of Education, Urumqi 830052, China.ORCID 0009-0003-9310-3905

Funding

Basic Research Funds for Universities of Xinjiang Uygur Autonomous Region XJEDU2026J011National College Students' Innovation and Entrepreneurship Training Program Project 202310758006National Natural Science Foundation of China 32301282Natural Science Foundation of Xinjiang Uygur Autonomous Region 2026D01B23Tianshan Talent Program in Xinjiang Uygur Autonomous Region 2024SNGGGCC014

6 · The paper itself

Abstract

Plant viral vectors are powerful tools for the transient expression of exogenous genes, enabling not only virus-induced gene silencing (VIGS) but also virus-induced genome editing (VIGE). However, technical systems capable of simultaneously achieving gene silencing and gene editing in cotton have been rarely reported to date. Therefore, the development of a virus vector system that can concurrently mediate both gene editing and gene silencing would provide a valuable platform for advancing functional genomics studies and molecular design breeding in cotton. To address this gap, we established a system in cotton that concurrently enables gene silencing and gene editing. This system utilizes cotton Cas9 overexpression (Cas9-OE) as a receptor and CLCrV and TRV as vectors for targeting the

Indexed as

CLCrVcottongene editinggene silencingTRV

Identifiers

PMID42075355

DOI10.3390/plants15081153

PMCPMC13119147

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.