Evidence map›Paper›PMID 42075320›Full record

ReviewMicroorganisms2026

Unveiling Lichen's Hidden Arsenal Against Multidrug Resistance: A Systematic Review of Their Essential Oils, Volatile Compounds and Extracts with Antimicrobial Applications.

Yasser Essadki, Soukaina El Amrani Zerrifi, Maria de Fátima Carvalho, Lillian Barros, Vitor Vasconcelos, Alexandre Campos, Fatima El Khalloufi, Brahim Oudra, Rosário Martins

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yasser EssadkiWater Sciences, Microbial Biotechnologies and Sustainability of Natural Resources Laboratory (Aquabiotech), Faculty of Sciences Semlalia of Marrakech, Cadi Ayyad University (UCA), Av. Prince My Abdellah, P.O. Box 2390, Marrakech 40000, Morocco.ORCID 0009-0006-4846-0075
Soukaina El Amrani ZerrifiWater Sciences, Microbial Biotechnologies and Sustainability of Natural Resources Laboratory (Aquabiotech), Faculty of Sciences Semlalia of Marrakech, Cadi Ayyad University (UCA), Av. Prince My Abdellah, P.O. Box 2390, Marrakech 40000, Morocco.
Maria de Fátima CarvalhoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, 4450-208 Porto, Portugal.ORCID 0000-0002-7181-0540
Lillian BarrosCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-9050-5189
Vitor VasconcelosInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, 4450-208 Porto, Portugal.ORCID 0000-0003-3585-2417
Alexandre CamposInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, 4450-208 Porto, Portugal.ORCID 0000-0003-4621-885X
Fatima El KhalloufiNatural Resources Engineering and Environmental Impacts Team, Multidisciplinary Research and Innovation Laboratory, Polydisciplinary Faculty of Khouribga, Sultan Moulay Slimane University of Beni Mellal, P.O. Box 145, Khouribga 25000, Morocco.ORCID 0000-0002-2922-8020
Brahim OudraWater Sciences, Microbial Biotechnologies and Sustainability of Natural Resources Laboratory (Aquabiotech), Faculty of Sciences Semlalia of Marrakech, Cadi Ayyad University (UCA), Av. Prince My Abdellah, P.O. Box 2390, Marrakech 40000, Morocco.ORCID 0000-0001-6295-9637
Rosário MartinsInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, 4450-208 Porto, Portugal.ORCID 0000-0002-9882-4651

Funding

European Union Marie Skłodowska-Curie Grant Agreement No 823860
6 · The paper itself

Abstract

The increase in multidrug resistance in microorganisms and the rise of emergent infectious diseases worldwide is a threat to human and animal health. Therefore, research on new molecules with antibiotic potential is a priority. Lichens have a unique secondary metabolism with relatively untapped potential, yet their essential oils (EOs) and volatile organic compounds (VOCs) remain a relatively untapped resource. This systematic review was conducted following PRISMA 2020 guidelines, with a comprehensive search performed in the Web of Science database for studies published up to 2023. From 254 identified records, six studies involving nine lichen species (

Indexed as

antimicrobial activityessential oilslichensmultidrug resistancePRISMA 2020secondary metabolitessystematic reviewvolatile organic compounds (VOCs)

Identifiers

PMID42075320
PMCPMC13118312

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.