Evidence map›Paper›PMID 42075311›Full record

ArticleMicroorganisms2026

Shotgun Metagenomic Characterization of Acne Microbiota Before and After Treatment with a Topical Biotechnological Phytocomplex: Understanding Skin Dysbiosis.

Adrià Cruells, Cristina Eguren, Aymée Robainas Barcia, Helena Martínez, Mohammed Sharaf, Carlos Ruiz, Antonio Sánchez-Baos, Nerea Carrón, Lola Bou, Montse Pérez and 2 more

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Adrià CruellsMicroomics Systems S.L., 08980 Sant Feliu de Llobregat, Spain.ORCID 0000-0002-1179-7997
Cristina EgurenClínica Eguren S.L.P., 28009 Madrid, Spain.ORCID 0000-0002-0357-9228
Aymée Robainas BarciaLaboratorio Reig Jofre, 08970 Sant Joan Despí, Spain.ORCID 0000-0001-9229-5376
Helena MartínezLaboratorio Reig Jofre, 08970 Sant Joan Despí, Spain.
Mohammed SharafLaboratorio Reig Jofre, 08970 Sant Joan Despí, Spain.
Carlos RuizLaboratorio Reig Jofre, 08970 Sant Joan Despí, Spain.ORCID 0009-0001-2662-2081
Antonio Sánchez-BaosMicroomics Systems S.L., 08980 Sant Feliu de Llobregat, Spain.
Nerea CarrónMicroomics Systems S.L., 08980 Sant Feliu de Llobregat, Spain.ORCID 0009-0003-2758-1431
Lola BouConsulta de Dermatología, 08006 Barcelona, Spain.
Montse PérezClínica Dermatológica de Moragas, 08034 Barcelona, Spain.
Raúl De LucasHospital Universitario La Paz, 28046 Madrid, Spain.
Aurora Guerra-TapiaConsulta Dermatóloga Guerra, 28027 Madrid, Spain.ORCID 0000-0002-5504-1382

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assessed the impact of a topical phytocomplex on the acne skin microbiota, encompassing bacterial, fungal, and phage communities. Skin samples obtained from participants exhibiting a positive response to the treatment were analyzed using high-throughput sequencing and bioinformatic approaches including taxonomic profiling, metagenome assembly, functional annotation, and phage identification. Results showed that after treatment, microbial diversity increased, reflecting a more balanced microbial composition.

Indexed as

acne vulgarisCutibacterium acnesMalasseziamicrobiomemicrobiotaquorum sensingshotgun

Identifiers

PMID42075311
PMCPMC13119204

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.