Evidence map›Paper›PMID 42075232›Full record

ArticleMicroorganisms2026

The Human Gut Microbiome Activity Is Resilient and Stable for up to Six Months: A Large Stool Metatranscriptomic Study.

Ryan Toma, Lan Hu, Nan Shen, Eric Patridge, Robert Wohlman, Guruduth Banavar, Momchilo Vuyisich

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan TomaViome Life Sciences, Inc., Bothell, WA 98011, USA.ORCID 0000-0003-4156-8316
Lan HuViome Life Sciences, Inc., New York, NY 10018, USA.ORCID 0009-0002-4383-7655
Nan ShenViome Life Sciences, Inc., New York, NY 10018, USA.
Eric PatridgeViome Life Sciences, Inc., New York, NY 10018, USA.ORCID 0000-0002-8638-3043
Robert WohlmanWashington Gastroenterology, Bellevue, WA 98004, USA.
Guruduth BanavarViome Life Sciences, Inc., New York, NY 10018, USA.
Momchilo VuyisichViome Life Sciences, Inc., Bothell, WA 98011, USA.ORCID 0000-0002-0531-6755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human microbiome influences health and disease through diverse biochemical and functional outputs (e.g., enzymes, structural proteins, metabolites, and other cellular components) that affect nearly every aspect of human physiology. Metatranscriptomics (MT), an unbiased RNA sequencing approach, is a high-throughput and high-content method that quantifies both gut microbial taxonomy and active biochemical functions. Because microbial community composition and gene expression are dynamic, understanding temporal variation in the gut metatranscriptome across multiple time scales is essential. Here, we report the temporal dynamics of gut microbiome species and functions using a large cohort (

Indexed as

colonoscopyfunctional stabilitygut microbiomelongitudinal analysismetatranscriptomicsmicrobial gene expressionmicrobiome resiliencemicrobiome stabilitytaxonomic stabilitytemporal dynamics

Identifiers

PMID42075232
PMCPMC13118932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.